Skin assessment
- Medical questionnaire and photo review
- Personalized treatment plan
- Prescription when appropriate
CA$175
per consultation
Modern Dermatology
Zoryve
Roflumilast cream
Prescription only
Zoryve prescribed online(Roflumilast cream)
Zoryve is a steroid-free prescription cream for plaque psoriasis, including skin folds. Share photos and your history online. A Canadian-licensed medical professional decides if it suits you.
Start my assessmentAt a glance
- Topical cream (roflumilast)
- For plaque psoriasis, including skin folds
- Steroid-free
Why Modern Dermatology
- Canadian-licensed medical professionals, 100% online
- Prescriptions sent to your pharmacy or delivered
- Follow-up and refills through your Care Team
Used forPsoriasis
Do not use Zoryve if you are allergic to roflumilast. Call your Care Team about swelling, hives, a spreading rash or changes in your mood.
Choosing the right plan for you
Your clinician decides how often you apply Zoryve, where and for how long. The plan depends on the areas of psoriasis and how thick the plaques are. Your clinician reviews it as your skin changes.
Considerations include
- Areas of psoriasis, such as folds or the body
- Thickness and scale of the plaques
- Age of the person being treated
- Past creams and how they worked
- Whether you want to avoid steroids
How Zoryve works
Zoryve calms the inflammation inside psoriasis plaques
Zoryve blocks PDE4, an enzyme that drives inflammation in the skin. With less PDE4 activity, cells make fewer inflammatory signals. Redness, scale and itch settle.
It works without a steroid, so it does not thin the skin. This is why it can suit folds and long-term use.
Modern Dermatology
Zoryve
Roflumilast cream
Prescription only
Recommended for
- Plaque psoriasis on the body
- Psoriasis in skin folds
- People who want a steroid-free cream
- Psoriasis that needs long-term control
- People who cannot use steroid creams well
Your clinician reviews your skin and history, and confirms that this treatment is right for you before prescribing.
Blocks PDE4
Quiets skin inflammation
Reduces redness and scale
Plaques look calmer
Eases itch
Less scratching
No steroid
No skin thinning
How it works.
- 01
Tell us about your skin
Complete a quick medical questionnaire and upload a few photos of your skin concerns. No appointment needed.
- 02
Get your personalized treatment plan
A Canadian-licensed medical professional will review your information and recommend a personalized treatment plan, including prescriptions when appropriate. Most conditions can be assessed without a video consultation.
- 03
Start your treatment
Get your prescribed medications delivered right to your door. Medication costs are billed separately from your consultation.
- 04
Follow up on your progress
At a follow-up, your clinician can review your progress, discuss side effects and adjust your treatment if needed.
Clear answers.
Have more questions? See our full FAQ or Contact us.
Still have questions? Reach our care team at 514 111 1111
Start my assessmentYes, when it is appropriate for you. You complete an assessment, and a Canadian-licensed medical professional reviews it and decides if Zoryve suits you.
Zoryve blocks PDE4, an enzyme that drives inflammation in the skin. This calms redness, scale and itch. It is not a steroid.
Some people see improvement within weeks. Plaques often keep improving over a few weeks to months. Your clinician decides how long you use it. Call your Care Team if there is no improvement.
Many people have less redness, scale and itch. Psoriasis can return, because Zoryve does not cure it. Your clinician may adjust the plan as your skin changes.
Diarrhea, headache, nausea and trouble sleeping can occur. Some people feel mild burning or pain where they apply it. Allergic reactions are rare. Tell your Care Team about any new symptom.
People allergic to roflumilast or to any ingredient in the cream should not use it. Tell your clinician about liver problems or past mood changes. Your clinician decides if it is safe.
Your clinician may suggest calcipotriol, a steroid such as betamethasone dipropionate or amcinonide, or calcipotriol with betamethasone. Apremilast by mouth and biologics such as adalimumab are other options. Your clinician picks what fits your psoriasis.
Often yes. Some people use it with another cream or with a biologic. Ask your Care Team before you combine treatments. Tell them about every product you use.
Data is limited. Tell your clinician if you are pregnant, planning pregnancy or breastfeeding. Your clinician weighs the benefits and risks. Your clinician chooses the safest plan for you.
Zoryve can suit skin folds and sensitive areas, where steroids are less suitable. Your clinician tells you which areas are right for you. Keep it away from your eyes and mouth.
Each consultation costs CA$175. Your pharmacy charges separately for medication. Ask your insurer whether your plan covers the prescribed treatment.
Zoryve is the only product listed in Canada for roflumilast cream. There is no generic yet. Your clinician writes the prescription.
Your clinician decides how long you use Zoryve and when to renew it. Your Care Team follows up with you, and you can message them with questions. Renewals depend on how your skin responds and on your clinician's review.
Simple pricing for your skin care.
Medication costs are separate. Ask your insurer whether your plan reimburses online consultations.
Start my assessment
Related treatments
Your clinician can suggest another option when this one is not the right fit.